21C MUSEUM HOTEL LOUISVILLE, Louisville – A Smart Stay in the City
Reserve directly with us
Up to 10% cheaper
than with Booking.com
Key details
About the Hotel
700 West Main Street,
Louisville,
Kentucky,
United States,
40202,
Kentucky
-
Steps from the Flame Run Glass Studio and Gallery
Loved by 21C Museum Hotel Louisville guests
Art installations
Spacious suites
Attentive staff
Delicious breakfast
Central location
Art and Hospitality
21C Museum Hotel Louisville blends contemporary art with luxury accommodations, creating a unique experience for guests. The hotel houses a 9,000-square-foot gallery that showcases rotating art exhibits, making it a living museum. Guests can enjoy various installations throughout the hotel, including a rooftop space featuring stunning views of downtown Louisville.
Accommodations
The hotel offers 91 spacious guest rooms, each equipped with custom furnishings and modern amenities. Rooms are designed to provide an immersive artistic experience, with some featuring original artworks. Luxurious bathrooms include walk-in showers and upscale bath products to enhance every stay.
Dining
Guests can savor culinary delights at the Proof on Main restaurant, which combines contemporary Southern cuisine with a curated wine list. The restaurant's interior features 20th-century art, creating an artistic dining atmosphere. Seasonal menu items emphasize local ingredients sourced from farmers and artisans in the area.
Business and Events
The hotel offers versatile meeting and event spaces, crafted to accommodate a range of gatherings. The 21C Gallery and other event rooms provide a creative backdrop for conferences, weddings, or private events. High-quality audiovisual equipment is available to ensure a seamless experience for all attendees.
Location and Nearby Attractions
Located in downtown Louisville, the hotel is steps away from popular attractions like the Kentucky Museum of Art and Craft. Guests can explore the local area with access to vibrant neighborhoods and cultural hotspots. The hotel serves as an excellent base for discovering the rich heritage and culinary scene of the city.
Highlights
Art: 9,000-square-foot gallery .
Dining: Proof on Main restaurant .
Events: 21C Gallery for meetings .
Location: Downtown Louisville attractions .
Rooms: 91 spacious guest rooms .
Experience: Original artworks in rooms .
Must-do experiences
Stop by the Big Four Bridge for stunning views of the river.
Try the Hot Brown at the Brown Hotel for a local culinary delight.
Visit the Muhammad Ali Center for a blend of culture and history.
Explore NuLu for unique shops and delicious local eateries.
Don't miss the Bourbon Trail for a taste of Kentucky's finest spirits.
View all
We are looking for rooms with better price.
Looks like there are no rooms available in this hotel for your dates.
You can check other available hotels or try other dates.
Check Dates & Room Rates
See what's available for your travel dates
Amenities
Thoughtfully designed amenities for a comfortable & memorable stay
General
Wi-Fi in public areas
24-hour reception
Wheelchair access
Services
Dry cleaning
Spa & Leisure
Sauna
Show more
21C Museum Hotel Louisville Location
700 West Main Street,
Louisville,
Kentucky,
United States,
40202,
Kentucky
Map view
700 West Main Street,
Louisville,
Kentucky,
United States,
40202,
Kentucky
City landmarks
Square
Fourth Street Live
2900 ft
Stadium
Louisville Slugger Field
5100 ft
Event hall
Kentucky International Convention Center
2600 ft
Park
Waterfront Park
1.0
mi
Church
Cathedral of the Assumption
2000 ft
Landmark
Freedom Hall
3600 ft
Museum
Thomas Edison House
1.3
mi
Landmark
Angel's Envy Distillery
1.0
mi
Landmark
Belle of Louisville Riverboats
2700 ft
Landmark
Jim Beam Urban Stillhouse
2800 ft
Landmark
Old Forester Distilling
2800 ft
Bridge
Big Four Bridge
1.4
mi
Library
Louisville Free Public Library
4700 ft
Bridge
The Big Four Bridge
1.4
mi
Landmark
West Main Historic District
1.4
mi
Museum
African American Heritage House Museum
1.3
mi
Landmark
KFC Yum Center
2.8
mi
Park
Falls of the Ohio State Park
2.4
mi
Nearby
Museum
Louisville Slugger Museum & Bat Factory
800 ft
Museum
Muhammad Ali Center
1100 ft
Museum
Kentucky Science Center
600 ft
Museum
The Frazier History Museum
1200 ft
Museum
Kentucky Museum of Art and Craft
300 ft
528 W Main St
Evan Williams Bourbon Experience
700 ft
Gallery
Flame Run Glass Studio and Gallery
1000 ft
500 W Main St
The Belvedere
900 ft
Night club
Jimmy Can't Dance
200 ft
801 W Main St
Michter's Fort Nelson Distillery
500 ft
Library
Sons of the American Revolution Genealogical Research Library
700 ft
120 N 10th St
Kentucky Peerless Distilling Co
1600 ft
Restaurants
Luigi's Pizzeria
300 ft
712 W Main St
Main Eatery
200 ft
643 W Main St
Boomers
400 ft
722 W Main St
Subway
500 ft
725 W Main St
Spinelli's Pizzeria
1800 ft
614 Baxter Ave Ste 4
Cravings Ala Carte
1400 ft
101 S 5th St Ste LL100
Spinellis Pizza
1800 ft
239 South 5th Street
Bazo's Fresh Mexican Grill
1600 ft
428 W Market St Located in Louisville's Central Business District.
Sunergos Coffee
1800 ft
231 S 5th St Located in Louisville's Central Business District.
Thelma's Deli
1700 ft
104 N 4th St Galt House
Jimmy John's
2100 ft
301 E Market St Unit 101
Explore Louisville
Explore Nearby Activities and Dining
Top Attractions
Activities
Dining
Entertainment
Louisville Slugger Museum & Bat Factory
3 minutes' walk
Interactive exhibits on baseball history and factory tours where bats are made. A must-see for sports enthusiasts.
Muhammad Ali Center
4 minutes' walk
Cultural center dedicated to the life of boxer Muhammad Ali. Features exhibits on social justice and peace.
Kentucky Science Center
2 minutes' walk
Hands-on science exhibits and an IMAX theater, perfect for families and curious minds of all ages.
The Frazier History Museum
5 minutes' walk
Showcases Kentucky's history through interactive exhibits and artifacts, including bourbon and civil rights themes.
Waterfront Park
20 minutes' walk
A scenic space with walking trails and picnic areas beside the Ohio River. Great for relaxation and outdoor fun.
Angel's Envy Distillery Tour
20 minutes' walk
Tour the distillery to learn about bourbon production with tastings included. Reservations are recommended.
Luigi's Pizzeria
2 minutes' walk
Casual eatery known for its authentic pizzas and pasta. A favorite among locals-try the Margherita!
Main Eatery
1 minute' walk
Cozy spot featuring local dishes with a modern twist. Ideal for brunch or quick bites anytime.
Fourth Street Live!
11 minutes' walk
Vibrant entertainment district with live music, bars, and dining options, hosting events year-round.
Belle of Louisville Riverboats
10 minutes' walk
Cruise along the Ohio River with sightseeing and themed entertainment. Family-friendly with a classic atmosphere.
Getting around
City Centre
Louisville23 min
·
1.2
mi
Airports
Louisville International Airport (SDF)15 min
·
6.2
mi
Unlock Early-Bird Deals
Grab Exclusive Rates Instantly
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Number of floors:
4
Number of rooms:
91
Guest Ratings & Reviews
Real Guest Experiences & Ratings
Pros
Art collection
Spacious rooms
Restaurant food
Cons
Parking fees
Elevator issues
Guest reviews
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.